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1918 pandemic influenza virus and Streptococcus pneumoniae coinfection results in activation of coagulation and widespread pulmonary thrombosis in mice and humans

To study bacterial coinfection following 1918 H1N1 influenza virus infection, mice were inoculated with the 1918 influenza virus followed by Streptococcus pneumoniae 72 h later. Coinfected mice exhibited markedly more severe disease, shortened survival time and more severe lung pathology, including...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Walters, Kathie-Anne, D'Agnillo, Felice, Sheng, Zong-Mei, Kindrachuk, Jason, Schwartzman, Louis M., Keustner, Rolf E., Chertow, Daniel S., Golding, Basil T., Taubenberger, Jeffery K., Kash, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789761/
https://ncbi.nlm.nih.gov/pubmed/26383585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4638
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