Atomic visualization of a flipped-back conformation of bisected glycans bound to specific lectins

Glycans normally exist as a dynamic equilibrium of several conformations. A fundamental question concerns how such molecules bind lectins despite disadvantageous entropic loss upon binding. Bisected glycan, a glycan possessing bisecting N-acetylglucosamine (GlcNAc), is potentially a good model for i...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Nagae, Masamichi, Kanagawa, Mayumi, Morita-Matsumoto, Kana, Hanashima, Shinya, Kizuka, Yasuhiko, Taniguchi, Naoyuki, Yamaguchi, Yoshiki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789653/
https://ncbi.nlm.nih.gov/pubmed/26971576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22973
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