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Atomic visualization of a flipped-back conformation of bisected glycans bound to specific lectins
Glycans normally exist as a dynamic equilibrium of several conformations. A fundamental question concerns how such molecules bind lectins despite disadvantageous entropic loss upon binding. Bisected glycan, a glycan possessing bisecting N-acetylglucosamine (GlcNAc), is potentially a good model for i...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4789653/ https://ncbi.nlm.nih.gov/pubmed/26971576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22973 |
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