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Ribozyme cleaves rex/tax mRNA and inhibits bovine leukemia virus expression.

Bovine leukemia virus (BLV) encodes at least two regulatory proteins, Rex and Tax. Tax, the transactivating protein, stimulates the long terminal repeat to promote viral transcription and may be involved in tumorigenesis. Rex is involved in the transition from early expression of regulatory proteins...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Cantor, G H, McElwain, T F, Birkebak, T A, Palmer, G H
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47895/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504287/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.10932
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