Ribozyme cleaves rex/tax mRNA and inhibits bovine leukemia virus expression.
Bovine leukemia virus (BLV) encodes at least two regulatory proteins, Rex and Tax. Tax, the transactivating protein, stimulates the long terminal repeat to promote viral transcription and may be involved in tumorigenesis. Rex is involved in the transition from early expression of regulatory proteins...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1993
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.10932 |
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