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Evaluation of a High-Throughput Peptide Reactivity Format Assay for Assessment of the Skin Sensitization Potential of Chemicals

The direct peptide reactivity assay (DPRA) is a validated method for in vitro assessment of the skin sensitization potential of chemicals. In the present work, we describe a peptide reactivity assay using 96-well plate format and systematically identified the optimal assay conditions for accurate an...

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Publicado en:Front Pharmacol
Main Authors: Wong, Chin Lin, Lam, Ai-Leen, Smith, Maree T., Ghassabian, Sussan
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789461/
https://ncbi.nlm.nih.gov/pubmed/27014067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00053
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