Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products

Microorganisms produce a wide range of natural products (NPs) with clinically and agriculturally relevant biological activities. In bacteria and fungi, genes encoding successive steps in a biosynthetic pathway tend to be clustered on the chromosome as biosynthetic gene clusters (BGCs). Historically,...

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Published in:Fungal Genet Biol
Main Authors: Li, Yong Fuga, Tsai, Kathleen J. S., Harvey, Colin J. B., Li, James Jian, Ary, Beatrice E., Berlew, Erin E., Boehman, Brenna L., Findley, David M., Friant, Alexandra G., Gardner, Christopher A., Gould, Michael P., Ha, Jae H., Lilley, Brenna K., McKinstry, Emily L., Nawal, Saadia, Parry, Robert C., Rothchild, Kristina W., Silbert, Samantha D., Tentilucci, Michael D., Thurston, Alana M., Wai, Rebecca B., Yoon, Yongjin, Aiyar, Raeka S., Medema, Marnix H., Hillenmeyer, Maureen E., Charkoudian, Louise K.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789092/
https://ncbi.nlm.nih.gov/pubmed/26808821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fgb.2016.01.012
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