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The 3D genome as moderator of chromosomal communication

Proper expression of genes requires communication with their regulatory elements that can be located elsewhere along the chromosome. The physics of chromatin fibers imposes a range of constraints on such communication. The molecular and biophysical mechanisms by which chromosomal communication is es...

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Vydáno v:Cell
Hlavní autoři: Dekker, Job, Mirny, Leonid
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788811/
https://ncbi.nlm.nih.gov/pubmed/26967279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.007
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