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Tristetraprolin mediates the anti-proliferative effects of metformin in breast cancer cells

Metformin, which is a drug commonly prescribed to treat type 2 diabetes, has anti-proliferative effects in cancer cells; however, the molecular mechanisms underlying this effect remain largely unknown. The aim is to investigate the role of tristetraprolin (TTP), an AU-rich element-binding protein, i...

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Bibliografski detalji
Izdano u:Breast Cancer Res Treat
Glavni autori: Pandiri, Indira, Chen, Yingqing, Joe, Yeonsoo, Kim, Hyo Jeong, Park, Jeongmin, Chung, Hun Taeg, Park, Jeong Woo
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788686/
https://ncbi.nlm.nih.gov/pubmed/26956973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-016-3742-y
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