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Enhanced allogeneic cellular responses to mismatched HLA-B antigens results in more efficient killing of HIV infected cells

Epidemiologic studies have demonstrated that HIV-1 discordant couples who share HLA-B alleles were more likely to transmit HIV-1. These data lead us to hypothesize that individuals who match at both HLA-B alleles should have a reduced allogeneic response than those who are not matched. We observed d...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: SABBAJ, Steffanie, SCANLON, Nicholas, DU, Victor Y., WANG, Yuge, TANG, Jianming, HUNTER, Eric, GOEPFERT, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788531/
https://ncbi.nlm.nih.gov/pubmed/26588705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000901
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