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Structural Basis of Resistance to Anti-Cytochrome bc(1) Complex Inhibitors: Implication for Drug Improvement

The emergence of drug resistance has devastating economic and social consequences, a testimonial of which is the rise and fall of inhibitors against the respiratory component cytochrome bc(1) complex, a time tested and highly effective target for disease control. Unfortunately, the mechanism of resi...

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Détails bibliographiques
Publié dans:Curr Pharm Des
Auteurs principaux: Esser, Lothar, Yu, Chang-An, Xia, Di
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788501/
https://ncbi.nlm.nih.gov/pubmed/23688079
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