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Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression
The tumor suppressors Retinoblastoma (Rb) and p53 are frequently inactivated in liver diseases, such as hepatocellular carcinomas (HCC) or infections with Hepatitis B or C viruses. Here, we discovered a novel role for Rb and p53 in xenobiotic metabolism, which represent a key function of the liver f...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4788452/ https://ncbi.nlm.nih.gov/pubmed/26967735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150064 |
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