The Combination of Marketed Antagonists of α1b-Adrenergic and 5-HT2A Receptors Inhibits Behavioral Sensitization and Preference to Alcohol in Mice: A Promising Approach for the Treatment of Alcohol Dependence

Alcohol-dependence is a chronic disease with a dramatic and expensive social impact. Previous studies have indicated that the blockade of two monoaminergic receptors, α1b-adrenergic and 5-HT2A, could inhibit the development of behavioral sensitization to drugs of abuse, a hallmark of drug-seeking an...

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Publicado en:PLoS One
Autores principales: Trovero, Fabrice, David, Sabrina, Bernard, Philippe, Puech, Alain, Bizot, Jean-Charles, Tassin, Jean-Pol
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788426/
https://ncbi.nlm.nih.gov/pubmed/26968030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151242
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