Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II

Proline isomerization greatly impacts biological signaling but is subtle and difficult to detect in proteins. We characterize this poorly understood regulatory mechanism for RNA polymerase II carboxyl terminal domain (CTD) phosphorylation state using novel, direct, and quantitative chemical tools. W...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :ACS Chem Biol
Главные авторы: Mayfield, Joshua E., Fan, Shuang, Wei, Shuo, Zhang, Mengmeng, Li, Bing, Ellington, Andrew D., Etzkorn, Felicia A., Zhang, Yan Jessie
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788383/
https://ncbi.nlm.nih.gov/pubmed/26332362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00296
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы