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Local Anesthetics and Antipsychotic Phenothiazines Interact Nonspecifically with Membranes and Inhibit Hexose Transporters in Yeast

Action mechanisms of anesthetics remain unclear because of difficulty in explaining how structurally different anesthetics cause similar effects. In Saccharomyces cerevisiae, local anesthetics and antipsychotic phenothiazines induced responses similar to those caused by glucose starvation, and they...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Uesono, Yukifumi, Toh-e, Akio, Kikuchi, Yoshiko, Araki, Tomoyuki, Hachiya, Takushi, Watanabe, Chihiro K., Noguchi, Ko, Terashima, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788134/
https://ncbi.nlm.nih.gov/pubmed/26757771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.183806
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