Targeting angiogenesis as a therapeutic means to reinforce osteocyte survival and prevent nonunions in the aftermath of radiotherapy

BACKGROUND: Radiotherapy (XRT) exerts detrimental collateral effects on bone tissue through mechanisms of vascular damage and impediments to osteocytes, ultimately predisposing patients to the debilitating problems of late pathologic fractures and nonunions. We posit that angiogenic therapy will rev...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Head Neck
Asıl Yazarlar: Donneys, Alexis, Nelson, Noah S., Page, Erin E., Deshpande, Sagar S., Felice, Peter A., Tchanque–Fossuo, Catherine N., Spiegel, Joshua P., Buchman, Steven R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788100/
https://ncbi.nlm.nih.gov/pubmed/24801669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.23744
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