The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum

Fragile X syndrome (FXS), the most common form of inherited intellectual disability, is caused by the silencing of the FMR1 gene encoding an RNA-binding protein (FMRP) mainly involved in translational control. We characterized the interaction between FMRP and the mRNA of GRK4, a member of the guanin...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Maurin, Thomas, Melko, Mireille, Abekhoukh, Sabiha, Khalfallah, Olfa, Davidovic, Laetitia, Jarjat, Marielle, D'Antoni, Simona, Catania, Maria Vincenza, Moine, Hervé, Bechara, Elias, Bardoni, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787806/
https://ncbi.nlm.nih.gov/pubmed/26250109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv801
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