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Phosphorylation state-dependent interaction between AKAP7δ/γ and phospholamban increases phospholamban phosphorylation

Changes in heart rate and contractility in response to sympathetic stimulation occur via activation of cAMP dependent protein kinase A (PKA), leading to phosphorylation of numerous substrates that alter Ca(2+) cycling. Phosphorylation of these substrates is coordinated by A-kinase anchoring proteins...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Signal
Egile Nagusiak: Rigatti, Marc, Le, Andrew V., Gerber, Claire, Moraru, Ion I., Dodge-Kafka, Kimberly L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787601/
https://ncbi.nlm.nih.gov/pubmed/26027516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.05.016
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