Human lung-resident macrophages express CB(1) and CB(2) receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors

Macrophages are pivotal effector cells in immune responses and tissue remodeling by producing a wide spectrum of mediators, including angiogenic and lymphangiogenic factors. Activation of cannabinoid receptor types 1 and 2 has been suggested as a new strategy to modulate angiogenesis in vitro and in...

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Bibliografiske detaljer
Udgivet i:J Leukoc Biol
Main Authors: Staiano, Rosaria I., Loffredo, Stefania, Borriello, Francesco, Iannotti, Fabio Arturo, Piscitelli, Fabiana, Orlando, Pierangelo, Secondo, Agnese, Granata, Francescopaolo, Lepore, Maria Teresa, Fiorelli, Alfonso, Varricchi, Gilda, Santini, Mario, Triggiani, Massimo, Di Marzo, Vincenzo, Marone, Gianni
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2016
Fag:
Spotlight on Leading Edge Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787289/
https://ncbi.nlm.nih.gov/pubmed/26467187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI1214-584R
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