Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue

Fluorescent antimicrobial peptides are promising structures for in situ, real-time imaging of fungal infection. Here we report a fluorogenic probe to image Aspergillus fumigatus directly in human pulmonary tissue. We have developed a fluorogenic Trp-BODIPY amino acid with a spacer-free C-C linkage b...

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Publicat a:Nat Commun
Autors principals: Mendive-Tapia, Lorena, Zhao, Can, Akram, Ahsan R., Preciado, Sara, Albericio, Fernando, Lee, Martin, Serrels, Alan, Kielland, Nicola, Read, Nick D, Lavilla, Rodolfo, Vendrell, Marc
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786873/
https://ncbi.nlm.nih.gov/pubmed/26956772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10940
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