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Antioxidants inhibit advanced glycosylation end-product-induced apoptosis by downregulation of miR-223 in human adipose tissue-derived stem cells

Advanced glycosylation end products (AGEs) are endogenous inflammatory mediators that induce apoptosis of mesenchymal stem cells. A potential mechanism includes increased generation of reactive oxygen species (ROS). MicroRNA-223 (miR-223) is implicated in the regulation of cell growth and apoptosis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Zhe, Li, Hongqiu, Guo, Ran, Wang, Qiushi, Zhang, Dianbao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786853/
https://ncbi.nlm.nih.gov/pubmed/26964642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23021
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