Impact of BCR-ABL transcript type on outcome in patients with chronic-phase CML treated with tyrosine kinase inhibitors

The most common breakpoint cluster region gene-Abelson murine leukemia viral oncogene homolog 1 (BCR-ABL) transcripts in chronic myeloid leukemia (CML) are e13a2 (b2a2) and e14a2 (b3a2). The impact of the type of transcript on response and survival after initial treatment with different tyrosine kin...

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Veröffentlicht in:Blood
Hauptverfasser: Jain, Preetesh, Kantarjian, Hagop, Patel, Keyur P., Gonzalez, Graciela Nogueras, Luthra, Rajyalakshmi, Shamanna, Rashmi Kanagal, Sasaki, Koji, Jabbour, Elias, Romo, Carlos Guillermo, Kadia, Tapan M., Pemmaraju, Naveen, Daver, Naval, Borthakur, Gautam, Estrov, Zeev, Ravandi, Farhad, O’Brien, Susan, Cortes, Jorge
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2016
Schlagworte:
Clinical Trials and Observations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786836/
https://ncbi.nlm.nih.gov/pubmed/26729897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-10-674242
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