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Vaginal Fibroblastic Cells from Women with Pelvic Organ Prolapse Produce Matrices with Increased Stiffness and Collagen Content

Pelvic organ prolapse (POP) is characterised by the weakening of the pelvic floor support tissues, and often by subsequent prolapse of the bladder outside the body, i.e. cystocele. The bladder is kept in place by the anterior vaginal wall which consists of a dense extracellular matrix rich in collag...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ruiz-Zapata, Alejandra M., Kerkhof, Manon H., Ghazanfari, Samaneh, Zandieh-Doulabi, Behrouz, Stoop, Reinout, Smit, Theo H., Helder, Marco N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786799/
https://ncbi.nlm.nih.gov/pubmed/26965792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22971
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