NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis

Hepatocellular carcinoma (HCC) is the second most common cause of cancer related death. Non-alcoholic fatty liver disease (NAFLD) affects a large proportion of the US population and is considered a metabolic predisposition to liver cancer (1-5). However, the role of adaptive immune responses in NAFL...

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Publicado no:Nature
Main Authors: Ma, Chi, Kesarwala, Aparna H., Eggert, Tobias, Medina-Echeverz, José, Kleiner, David E., Jin, Ping, Stroncek, David F., Terabe, Masaki, Kapoor, Veena, ElGindi, Mei, Han, Miaojun, Thornton, Angela M., Zhang, Haibo, Egger, Michèle, Luo, Ji, Felsher, Dean W., McVicar, Daniel W., Weber, Achim, Heikenwalder, Mathias, Greten, Tim F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786464/
https://ncbi.nlm.nih.gov/pubmed/26934227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16969
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