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Cyclin B Translation Depends on mTOR Activity after Fertilization in Sea Urchin Embryos
The cyclin B/CDK1 complex is a key regulator of mitotic entry. Using PP242, a specific ATP-competitive inhibitor of mTOR kinase, we provide evidence that the mTOR signalling pathway controls cyclin B mRNA translation following fertilization in Sphaerechinus granularis and Paracentrotus lividus. We s...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4786324/ https://ncbi.nlm.nih.gov/pubmed/26962866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150318 |
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