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Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression

The nuclear receptors REV-ERBα and REV-ERBβ are transcription factors that play pivotal roles in the regulation of the circadian rhythm and various metabolic processes. The circadian rhythm is an endogenous mechanism, which generates entrainable biological changes that follow a 24-hour period. It re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Amador, Ariadna, Wang, Yongjun, Banerjee, Subhashis, Kameneka, Theodore M., Solt, Laura A., Burris, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786293/
https://ncbi.nlm.nih.gov/pubmed/26963516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151014
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