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Parameterization for In-Silico Modeling of Ion Channel Interactions with Drugs

Since the first Hodgkin and Huxley ion channel model was described in the 1950s, there has been an explosion in mathematical models to describe ion channel function. As experimental data has become richer, models have concomitantly been improved to better represent ion channel kinetic processes, alt...

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Bibliographic Details
Published in:PLoS One
Main Authors: Moreno, Jonathan D., Lewis, Timothy J., Clancy, Colleen E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786197/
https://ncbi.nlm.nih.gov/pubmed/26963710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150761
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