Pathway Implications of Aberrant Global Methylation in Adrenocortical Cancer

CONTEXT: Adrenocortical carcinomas (ACC) are a rare tumor type with a poor five-year survival rate and limited treatment options. OBJECTIVE: Understanding of the molecular pathogenesis of this disease has been aided by genomic analyses highlighting alterations in TP53, WNT, and IGF signaling pathway...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Legendre, Christophe R., Demeure, Michael J., Whitsett, Timothy G., Gooden, Gerald C., Bussey, Kimberly J., Jung, Sungwon, Waibhav, Tembe, Kim, Seungchan, Salhia, Bodour
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786116/
https://ncbi.nlm.nih.gov/pubmed/26963385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150629
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