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Nigrostriatal Dopamine Acting on Globus Pallidus Regulates Sleep

Lesions of the globus pallidus externa (GPe) produce a profound sleep loss (∼45%) in rats, suggesting that GPe neurons promote sleep. As GPe neuronal activity is enhanced by dopamine (DA) from the substantia nigra pars compacta (SNc), we hypothesized that SNc DA via the GPe promotes sleep. To test t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cereb Cortex
Prif Awduron: Qiu, Mei-Hong, Yao, Qiao-Ling, Vetrivelan, Ramalingam, Chen, Michael C., Lu, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785943/
https://ncbi.nlm.nih.gov/pubmed/25316334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhu241
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