Nigrostriatal Dopamine Acting on Globus Pallidus Regulates Sleep

Lesions of the globus pallidus externa (GPe) produce a profound sleep loss (∼45%) in rats, suggesting that GPe neurons promote sleep. As GPe neuronal activity is enhanced by dopamine (DA) from the substantia nigra pars compacta (SNc), we hypothesized that SNc DA via the GPe promotes sleep. To test t...

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Bibliographic Details
Published in:Cereb Cortex
Main Authors: Qiu, Mei-Hong, Yao, Qiao-Ling, Vetrivelan, Ramalingam, Chen, Michael C., Lu, Jun
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785943/
https://ncbi.nlm.nih.gov/pubmed/25316334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhu241
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