Nigrostriatal Dopamine Acting on Globus Pallidus Regulates Sleep

Lesions of the globus pallidus externa (GPe) produce a profound sleep loss (∼45%) in rats, suggesting that GPe neurons promote sleep. As GPe neuronal activity is enhanced by dopamine (DA) from the substantia nigra pars compacta (SNc), we hypothesized that SNc DA via the GPe promotes sleep. To test t...

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Bibliografske podrobnosti
izdano v:Cereb Cortex
Main Authors: Qiu, Mei-Hong, Yao, Qiao-Ling, Vetrivelan, Ramalingam, Chen, Michael C., Lu, Jun
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785943/
https://ncbi.nlm.nih.gov/pubmed/25316334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhu241
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