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Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage

The retinal pigment epithelial cell (RPE cell) layer protects the photoreceptors of the retina against oxidative stress. The decline of this capacity is believed to be a major factor in the impairment of vision in age-related macular degeneration. Exposure of human adult RPE cells to UV light at pre...

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Detalhes bibliográficos
Main Authors: Gao, Xiangqun, Talalay, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC478590/
https://ncbi.nlm.nih.gov/pubmed/15229324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403886101
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