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Repression of Pumilio protein expression by Rbfox1 promotes germ cell differentiation

RNA-binding Fox (Rbfox) proteins have well-established roles in regulating alternative splicing, but specific Rbfox isoforms lack nuclear localization signals and accumulate in the cytoplasm. The potential splicing-independent functions of these proteins remain unknown. Here we demonstrate that cyto...

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Bibliografiske detaljer
Udgivet i:Dev Cell
Main Authors: Carreira-Rosario, Arnaldo, Bhargava, Varsha, Hillebrand, Jens, Kollipara, Rahul K., Ramaswami, Mani, Buszczak, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785839/
https://ncbi.nlm.nih.gov/pubmed/26954550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.02.010
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