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The potential of deferasirox as a novel therapeutic modality in gastric cancer

BACKGROUND: Iron is a crucial element for cell proliferation, growth, and metabolism. However, excess iron and altered iron metabolism are both associated with tumor initiation and tumor growth. Deferasirox is an oral iron chelator. Although some studies have indicated that deferasirox is a promisin...

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Vydáno v:World J Surg Oncol
Hlavní autoři: Choi, Jung Hye, Kim, Jung Soon, Won, Young Woong, Uhm, Jieun, Park, Byeong Bae, Lee, Young Yiul
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785730/
https://ncbi.nlm.nih.gov/pubmed/26965928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-016-0829-1
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