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Thyroid hormone receptor α is a molecular switch of cardiac function between fetal and postnatal life

Thyroid hormones are involved in the regulation of many physiological processes and regulate gene transcription by binding to their nuclear receptors TRα and TRβ. In the absence of triiodothyronine (T3), the unliganded receptors (aporeceptors) do bind DNA and repress the transcription of target gene...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Mai, Wilfried, Janier, Marc F., Allioli, Nathalie, Quignodon, Laure, Chuzel, Thomas, Flamant, Frédéric, Samarut, Jacques
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC478572/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15240882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401843101
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