Direct transfer of transforming growth factor beta 1 gene into arteries stimulates fibrocellular hyperplasia.

The arterial wall responds to thrombosis or mechanical injury through the induction of specific gene products that increase cellular proliferation and connective tissue formation. These changes result in intimal hyperplasia that is observed in restenosis and the early phases of atherosclerosis. Tran...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Nabel, E G, Shum, L, Pompili, V J, Yang, Z Y, San, H, Shu, H B, Liptay, S, Gold, L, Gordon, D, Derynck, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47857/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10759
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