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The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity

In prokaryotes, two DNA glycosylases recognize and excise oxidized pyrimidines: endonuclease III (Nth) and endonuclease VIII (Nei). The oxidized purine 8-oxoguanine, on the other hand, is recognized by Fpg (also known as MutM), a glycosylase that belongs to the same family as Nei. The recent availab...

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Bibliografiske detaljer
Main Authors: Doublié, Sylvie, Bandaru, Viswanath, Bond, Jeffrey P., Wallace, Susan S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC478564/
https://ncbi.nlm.nih.gov/pubmed/15232006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402051101
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