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Nuclear condensation during mouse erythropoiesis requires caspase-3-mediated nuclear opening

Mammalian erythropoiesis involves chromatin condensation that is initiated in the early stage of terminal differentiation. The mechanisms of chromatin condensation during erythropoiesis are unclear. Here, we show that the mouse erythroblast forms large, transient, and recurrent nuclear openings that...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Zhao, Baobing, Mei, Yang, Schipma, Matthew J, Roth, Eric Wayne, Bleher, Reiner, Rappoport, Joshua Z., Wickrema, Amittha, Yang, Jing, Ji, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785602/
https://ncbi.nlm.nih.gov/pubmed/26954545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.02.001
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