Rv2686c-Rv2687c-Rv2688c, an ABC Fluoroquinolone Efflux Pump in Mycobacterium tuberculosis

The Mycobacterium tuberculosis Rv2686c-Rv2687c-Rv2688c operon, encoding an ABC transporter, conferred resistance to ciprofloxacin and, to a lesser extent, norfloxacin, moxifloxacin, and sparfloxacin to Mycobacterium smegmatis. The resistance level decreased in the presence of the efflux pump inhibit...

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Autors principals: Pasca, Maria Rosalia, Guglierame, Paola, Arcesi, Fabio, Bellinzoni, Marco, De Rossi, Edda, Riccardi, Giovanna
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC478549/
https://ncbi.nlm.nih.gov/pubmed/15273144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.3175-3178.2004
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