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Interferon Lambda 4 Genotype Is Associated With Jaundice and Elevated Aminotransferase Levels During Acute Hepatitis C Virus Infection: Findings From the InC3 Collaborative

Symptomatic acute HCV infection and interferon lambda 4 (IFNL4) genotypes are important predictors of spontaneous viral clearance. Using data from a multicohort database (Injecting Cohorts [InC3] Collaborative), we establish an independent association between host IFNL4 genotype and symptoms of acut...

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Vydáno v:Open Forum Infect Dis
Hlavní autoři: Page, Kimberly, Mirzazadeh, Ali, Rice, Thomas M., Grebely, Jason, Kim, Arthur Y., Cox, Andrea L., Morris, Meghan D., Hellard, Margaret, Bruneau, Julie, Shoukry, Naglaa H., Dore, Gregory J., Maher, Lisa, Lloyd, Andrew R., Lauer, Georg, Prins, Maria, McGovern, Barbara H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785397/
https://ncbi.nlm.nih.gov/pubmed/26973850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofw024
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