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DBS-platform for biomonitoring and toxicokinetics of toxicants: proof of concept using LC-MS/MS analysis of fipronil and its metabolites in blood

A simple, sensitive and high throughput LC-MS/MS method was developed and validated for quantification of fipronil, fipronil sulfone and fipronil desulfinyl in rat and human dried blood spots (DBS). DBS samples were prepared by spiking 10 μl blood on DMPK-C cards followed by drying at room temperatu...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Raju, Kanumuri Siva Rama, Taneja, Isha, Rashid, Mamunur, Sonkar, Ashish Kumar, Wahajuddin, Muhammad, Singh, Sheelendra Pratap
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785372/
https://ncbi.nlm.nih.gov/pubmed/26960908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22447
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