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Serum Removal from Culture Induces Growth Arrest, Ploidy Alteration, Decrease in Infectivity and Differential Expression of Crucial Genes in Leishmania infantum Promastigotes

Leishmania infantum is one of the species responsible for visceral leishmaniasis. This species is distributed basically in the Mediterranean basin. A recent outbreak in humans has been reported in Spain. Axenic cultures are performed for most procedures with Leishmania spp. promastigotes. This model...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Alcolea, Pedro J., Alonso, Ana, Moreno-Izquierdo, Miguel A., Degayón, María A., Moreno, Inmaculada, Larraga, Vicente
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784933/
https://ncbi.nlm.nih.gov/pubmed/26959417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150172
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