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Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals

Tissue integrity and homeostasis often rely on the proliferation of stem cells or differentiated cells to replace lost, aged, or damaged cells. Recently, we described an alternative source of cell replacement- the expansion of resident, non-dividing diploid cells by wound-induced polyploidization (W...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Losick, Vicki P., Jun, Albert S., Spradling, Allan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784922/
https://ncbi.nlm.nih.gov/pubmed/26958853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151251
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