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The Vascular Endothelial Growth Factor Inhibitors Ranibizumab and Aflibercept Markedly Increase Expression of Atherosclerosis-Associated Inflammatory Mediators on Vascular Endothelial Cells

INTRODUCTION: Recent studies have suggested that the VEGF inhibitors, Ranibizumab and Aflibercept may be associated with an excess of cardiovascular events, potentially driven by increasing atheroma instability, leading to plaque rupture and clinical events. Inflammation plays a key role in the prog...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Arnott, Clare, Punnia-Moorthy, Gaya, Tan, Joanne, Sadeghipour, Sara, Bursill, Christina, Patel, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784900/
https://ncbi.nlm.nih.gov/pubmed/26959822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150688
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