The Vascular Endothelial Growth Factor Inhibitors Ranibizumab and Aflibercept Markedly Increase Expression of Atherosclerosis-Associated Inflammatory Mediators on Vascular Endothelial Cells

INTRODUCTION: Recent studies have suggested that the VEGF inhibitors, Ranibizumab and Aflibercept may be associated with an excess of cardiovascular events, potentially driven by increasing atheroma instability, leading to plaque rupture and clinical events. Inflammation plays a key role in the prog...

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Опубликовано в: :PLoS One
Главные авторы: Arnott, Clare, Punnia-Moorthy, Gaya, Tan, Joanne, Sadeghipour, Sara, Bursill, Christina, Patel, Sanjay
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784900/
https://ncbi.nlm.nih.gov/pubmed/26959822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150688
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