Resolution of the HLA-DRB6 puzzle: a case of grafting a de novo-generated exon on an existing gene.
HLA-DRB6, one of the human major histocompatibility complex genes, lacks exon 1, which normally codes for the leader and the first four amino acid residues of the mature protein. Because it also lacks the HLA promoter, it was surprising to find that the gene is transcribed at a low level in a chimpa...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1993
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47849/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248165/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10720 |
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