Comparison of Gene Expression Profiles of Candida albicans Azole-Resistant Clinical Isolates and Laboratory Strains Exposed to Drugs Inducing Multidrug Transporters

Azole resistance in Candida albicans can be due to upregulation of multidrug transporters belonging to ABC (ATP-binding cassette) transporters (CDR1 and CDR2) or major facilitators (CaMDR1). Upregulation of these genes can also be achieved by exposure to fluphenazine, resulting in specific upregulat...

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Main Authors: Karababa, Mahir, Coste, Alix T., Rognon, Bénédicte, Bille, Jacques, Sanglard, Dominique
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC478486/
https://ncbi.nlm.nih.gov/pubmed/15273122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.8.3064-3079.2004
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