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Cellular epigenetics: effects of passage history on competence of cells for "spontaneous" transformation.

"Spontaneous" neoplastic transformation of cells in culture has been shown to be an adaptive response to moderate physiological constraints such as contact inhibition and lowered concentrations of serum. These are the same constraints that promote normal differentiation of a variety of cel...

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Detalhes bibliográficos
Autor principal: Rubin, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47848/
https://ncbi.nlm.nih.gov/pubmed/8248164
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