Autoimmune response to transthyretin in juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA) is the most common pediatric rheumatological condition. Although it has been proposed that JIA has an autoimmune component, the autoantigens are still unknown. Using biochemical and proteomic approaches, we identified the molecular chaperone transthyretin (TTR) as...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Clement, Cristina C., Moncrieffe, Halima, Lele, Aditi, Janow, Ginger, Becerra, Aniuska, Bauli, Francesco, Saad, Fawzy A., Perino, Giorgio, Montagna, Cristina, Cobelli, Neil, Hardin, John, Stern, Lawrence J., Ilowite, Norman, Porcelli, Steven A., Santambrogio, Laura
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784708/
https://ncbi.nlm.nih.gov/pubmed/26973882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85633
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