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Contact activation of C3 enables tethering between activated platelets and polymorphonuclear leukocytes via CD11b/CD18
Complement component C3 has a potential role in thrombotic pathologies. It is transformed, without proteolytic cleavage, into C3(H(2)O) upon binding to the surface of activated platelets. We hypothesise that C3(H(2)O) bound to activated platelets and to platelet-derived microparticles (PMPs) contrib...
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| Publicado no: | Thromb Haemost |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4784683/ https://ncbi.nlm.nih.gov/pubmed/26293614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH15-02-0162 |
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