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Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein Cargos

The hydrophilic nature of peptides and proteins renders them impermeable to cell membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics across the plasma membrane or epithelial and endothelial barriers, a permeation enhancing strategy must be employed. Cell-penetrat...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kristensen, Mie, Birch, Ditlev, Mørck Nielsen, Hanne
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783919/
https://ncbi.nlm.nih.gov/pubmed/26840305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17020185
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