Icaritin Inhibits Collagen Degradation-Related Factors and Facilitates Collagen Accumulation in Atherosclerotic Lesions: A Potential Action for Plaque Stabilization

Most acute coronary syndromes result from rupture of vulnerable atherosclerotic plaques. The collagen content of plaques may critically affect plaque stability. This study tested whether Icaritin (ICT), an intestinal metabolite of Epimedium-derived flavonoids, could alter the collagen synthesis/degr...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Zhang, Zong-Kang, Li, Jie, Yan, De-Xin, Leung, Wing-Nang, Zhang, Bao-Ting
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783903/
https://ncbi.nlm.nih.gov/pubmed/26828485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17020169
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