The Metabolic Fate of ortho-Quinones Derived from Catecholamine Metabolites

ortho-Quinones are produced in vivo through the oxidation of catecholic substrates by enzymes such as tyrosinase or by transition metal ions. Neuromelanin, a dark pigment present in the substantia nigra and locus coeruleus of the brain, is produced from dopamine (DA) and norepinephrine (NE) via an i...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Ito, Shosuke, Yamanaka, Yuta, Ojika, Makoto, Wakamatsu, Kazumasa
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783898/
https://ncbi.nlm.nih.gov/pubmed/26828480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17020164
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