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Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study

The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Abdullah, Nor Hayati, Thomas, Noel Francis, Sivasothy, Yasodha, Lee, Vannajan Sanghiran, Liew, Sook Yee, Noorbatcha, Ibrahim Ali, Awang, Khalijah
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783877/
https://ncbi.nlm.nih.gov/pubmed/26907251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17020143
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